Patrick Chene: search on Z-Library

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1

Inhibiting the p53–MDM2 interaction: an important target for cancer therapy

Chène, Patrick

Journal:

Nature Reviews Cancer

Year:

2003

Language:

english

File:

PDF, 1.08 MB

english, 2003

2

Potentiality of front-face fluorescence and mid-infrared spectroscopies coupled with partial least square regression to predict lipid oxidation in pound cakes during storage

Nhouchi, Zeineb, Botosoa, Eliot Patrick, Chene, Christine, Karoui, Romdhane

Journal:

Year:

2019

Language:

english

File:

PDF, 761 KB

english, 2019

3

Discovery of a novel class of highly potent inhibitors of the p53–MDM2 interaction by structure-based design starting from a conformational argument

Furet, Pascal, Masuya, Keiichi, Kallen, Joerg, Stachyra-Valat, Thérèse, Ruetz, Stephan, Guagnano, Vito, Holzer, Philipp, Mah, Robert, Stutz, Stefan, Vaupel, Andrea, Chène, Patrick, Jeay, Sébastien, Sc

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 816 KB

english, 2016

4

The TEAD4-YAP/TAZ Protein-Protein Interaction: Expected Similarities and Unexpected Differences

Hau, Jean Christophe, Erdmann, Dirk, Mesrouze, Yannick, Furet, Pascal, Fontana, Patrizia, Zimmermann, Catherine, Schmelzle, Tobias, Hofmann, Francesco, Chène, Patrick

Journal:

Year:

2013

Language:

english

File:

PDF, 990 KB

english, 2013

5

Aib-based peptide backbone as scaffolds for helical peptide mimics

Raja Banerjee, Gautam Basu, Siddhartha Roy, Patrick Chène

Journal:

Chemical Biology & Drug Design

Year:

2002

Language:

english

File:

PDF, 162 KB

english, 2002

6

Characterization of p53 mutants identified in human tumors with a missense mutation in the tetramerization domain

Christiane Rollenhagen, Patrick Chène

Journal:

International Journal of Cancer

Year:

1998

Language:

english

File:

PDF, 127 KB

english, 1998

7

Oligomerization of p53 upon Cooperative DNA Binding: Towards a Structural Understanding of p53 Function

Patrick Chene, Wolfgang Jahnke

Journal:

Angewandte Chemie International Edition

Year:

2002

Language:

english

File:

PDF, 92 KB

english, 2002

8

Role of Isoleucine-164 at the Active Site of Rubisco fromRhodospirillum rubrum

Patrick Chène, Anthony G. Day, Alan R. Fersht

Journal:

Biochemical and Biophysical Research Communications

Year:

1997

Language:

english

File:

PDF, 109 KB

english, 1997

9

A critical assessment of the synthesis and biological activity of p53/Hdm2 stapled peptide inhibitors

Wallbrecher, Rike, Chène, Patrick, Ruetz, Stephan, Stachyra, Therese, Vorherr, Thomas, Brock, Roland

Journal:

British Journal of Pharmacology

Year:

2017

Language:

english

File:

PDF, 564 KB

english, 2017

10

Coupling of the antennapedia third helix to a potent antagonist of the p53/hdm2 protein–protein interaction

Carlos Garcı́a-Echeverrı́a, Pascal Furet, Patrick Chène

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2001

Language:

english

File:

PDF, 117 KB

english, 2001

11

Catalytic inhibition of topoisomerase II by a novel rationally designed ATP-competitive purine analogue

Patrick Chène, Joëlle Rudloff, Joseph Schoepfer, Pascal Furet, Peter Meier, Zhiyan Qian, Jean-Marc Schlaeppi, Rita Schmitz, Thomas Radimerski

Journal:

BMC Chemical Biology

Year:

2009

Language:

english

File:

PDF, 2.36 MB

english, 2009

12

Mutation of threonine-53 alters the kinetic properties of rubisco from Rhodospirillum rubrum

Patrick Chène, Christiane Chène

Journal:

Journal of Plant Physiology

Year:

1998

Language:

english

File:

PDF, 484 KB

english, 1998

13

Tobacco Addiction and HIV Infection: Toward the Implementation of Cessation Programs. ANRS CO3 Aquitaine Cohort

Benard, Antoine, Bonnet, Fabrice, Tessier, Jean-François, Fossoux, Helene, Dupon, Michel, Mercie, Patrick, Ragnaud, Jean-Marie, Viallard, Jean-François, Dabis, François, Chene, Genevieve

Journal:

AIDS PATIENT CARE and STDs

Year:

2007

Language:

english

File:

PDF, 125 KB

english, 2007

14

Decline in locomotor functions over time in HIV-infected patients

Richert, Laura, Brault, Mathilde, Mercié, Patrick, Dauchy, Frédéric-Antoine, Bruyand, Mathias, Greib, Carine, Dabis, François, Bonnet, Fabrice, Chêne, Geneviève, Dehail, Patrick

Journal:

Year:

2014

Language:

english

File:

PDF, 334 KB

english, 2014

15

Immunological markers after long-term treatment interruption in chronically HIV-1 infected patients with CD4 cell count above 400 × 106 cells/l

Thiébaut, Rodolphe, Pellegrin, Isabelle, Chêne, Geneviève, Viallard, Jean François, Fleury, Hervé, Moreau, Jean François, Pellegrin, Jean Luc, Blanco, Patrick

Journal:

Year:

2005

Language:

english

File:

PDF, 166 KB

english, 2005

16

Clinical development of placental malaria vaccines and immunoassays harmonization: a workshop report

Chêne, Arnaud, Houard, Sophie, Nielsen, Morten A., Hundt, Sophia, D’Alessio, Flavia, Sirima, Sodiomon B., Luty, Adrian J. F., Duffy, Patrick, Leroy, Odile, Gamain, Benoit, Viebig, Nicola K.

Journal:

Malaria Journal

Year:

2016

Language:

english

File:

PDF, 1.13 MB

english, 2016

17

Cellular characterisation of p53 mutants with a single missense mutation in the β-strand 326–333 and correlation of their cellular activities with in vitro properties

Patrick Chène, Elisabeth Bechter

Journal:

Journal of Molecular Biology

Year:

1999

Language:

english

File:

PDF, 319 KB

english, 1999

18

Interferon-gamma with peginterferon alpha-2a and ribavirin in nonresponder patients with chronic hepatitis C (ANRS HC16 GAMMATRI)

Couzigou, Patrice, Pérusat, Sophie, Bourlière, Marc, Trimoulet, Pascale, Poynard, Thierry, Leroy, Vincent, Marcellin, Patrick, Foucher, Juliette, Bronowicki, Jean-Pierre, Chêne, Geneviève

Journal:

Journal of Gastroenterology and Hepatology

Year:

2013

Language:

english

File:

PDF, 385 KB

english, 2013

19

NS3 Helicases as Drug Targets

Journal:

Current Chemical Biology

Year:

2009

Language:

english

File:

PDF, 664 KB

english, 2009

20

Adaptation of the bound intrinsically disordered protein YAP to mutations at the YAP:TEAD interface

Mesrouze, Yannick, Bokhovchuk, Fedir, Izaac, Aude, Meyerhofer, Marco, Zimmermann, Catherine, Fontana, Patrizia, Schmelzle, Tobias, Erdmann, Dirk, Furet, Pascal, Kallen, Joerg, Chène, Patrick

Journal:

Protein Science

Year:

2018

Language:

english

File:

PDF, 1.36 MB

english, 2018

21

Discovery of Potent and Selective Antibody–Drug Conjugates with Eg5 Inhibitors through Linker and Payload Optimization

Karpov, Alexei S., Nieto-Oberhuber, Cristina M., Abrams, Tinya, Beng-Louka, Edwige, Blanco, Enrique, Chamoin, Sylvie, Chene, Patrick, Dacquignies, Isabelle, Daniel, Dylan, Dillon, Michael P., Doumampo

Journal:

ACS Medicinal Chemistry Letters

Year:

2019

File:

PDF, 1.50 MB

2019

22

ChemInform Abstract: Oligomerization of p53 upon Cooperative DNA Binding: Towards a Structural Understanding of p53 Function

Patrick Chene, Wolfgang Jahnke

Journal:

Year:

2002

File:

PDF, 25 KB

2002

23

Neutralizing antibodies to interferon-α and circulating interferon in patients with chronic hepatitis C non-responding to pegylated interferon plus ribavirin re-treated by pegylated interferon-α-2a and ribavirin (ANRS HC16 GAMMATRI substudy*)

Philippe Halfon, Sophie Pérusat, Marc Bourlière, Jean-Pierre Bronowicki, Pascale Trimoulet, Yves Benhamou, Vincent Leroy, Patrick Marcellin, Juliette Foucher, Guillaume Penaranda, Geneviève Chêne, Pat

Journal:

Journal of Medical Virology

Year:

2010

Language:

english

File:

PDF, 71 KB

english, 2010

24

p53 as a drug target in cancer therapy

Chène, Patrick

Journal:

Expert Opinion on Therapeutic Patents

Year:

2001

Language:

english

File:

PDF, 323 KB

english, 2001

25

Challenges in design of biochemical assays for the identification of small molecules to target multiple conformations of protein kinases

Journal:

Drug Discovery Today

Year:

2008

Language:

english

File:

PDF, 445 KB

english, 2008

26

Factors influencing the inhibition of protein kinases

Brockhoff, Marielle, Hau, Jean-Christophe, Fontana, Patrizia, Zimmermann, Catherine, De Pover, Alain, Erdmann, Dirk, Chène, Patrick

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 842 KB

english, 2012

27

Can biochemistry drive drug discovery beyond simple potency measurements?

Journal:

Drug Discovery Today

Year:

2012

Language:

english

File:

PDF, 376 KB

english, 2012

28

Investigation of alkali borosilicate glass durability using tritium tracing, β-autoradiography, scanning electron microscopy and ion beam analysis

Jacques Chêne, Patrick Trocellier

Journal:

Journal of Non-Crystalline Solids

Year:

2004

Language:

english

File:

PDF, 798 KB

english, 2004

29

Study of the cytotoxic effect of a peptidic inhibitor of the p53–hdm2 interaction in tumor cells

Patrick Chène, Jean Fuchs, Ilaria Carena, Pascal Furet, Carlos Garcı́a Echeverrı́a

Journal:

Year:

2002

Language:

english

File:

PDF, 227 KB

english, 2002

30

Peroxisome Proliferator Activating Receptor Alpha and Gamma Polymorphisms and Metabolic Abnormalities in HIV-Infected Patients Receiving Highly Active Antiretroviral Therapy: The ANRS CO8 APROCO-COPILOTE Study

Nazih, Hassan, Raffi, François, Taïeb, Audrey, Reynes, Jacques, Choutet, Patrick, Cassuto, Jill-Patrick, Ferry, Tristan, Chêne, Geneviève, Leport, Catherine, Bard, for the APROCO-COPILOTE (ANRS, Jean-

Journal:

AIDS Research and Human Retroviruses

Year:

2012

Language:

english

File:

PDF, 1.25 MB

english, 2012

31

TT virus infection during chronic hepatitis C

Trimoulet, Pascale, Ledinghen, Victor, Ekouevi, Didier, Bernard, Pierre-Henri, Merel, Patrick, Chene, Genevieve, Couzigou, Patrice, Fleury, Herve

Journal:

American Journal of Gastroenterology

Year:

2000

Language:

english

File:

PDF, 49 KB

english, 2000

32

Functional analyses of a unique p53 germline mutant (y236Δ) associated with a familial brain tumor syndrome

Patrick Chène, Katherine Ory, Daniela Rüedi, Thierry Soussi, Monika E. Hegi

Journal:

International Journal of Cancer

Year:

1999

Language:

english

File:

PDF, 112 KB

english, 1999

33

2-Amino-aryl-7-aryl-benzoxazoles as potent, selective and orally available JAK2 inhibitors

Marc Gerspacher, Pascal Furet, Carole Pissot-Soldermann, Christoph Gaul, Philipp Holzer, Eric Vangrevelinghe, Marc Lang, Dirk Erdmann, Thomas Radimerski, Catherine H. Regnier, Patrick Chene, Alain De

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 1.56 MB

english, 2010

34

Discovery of dihydroisoquinolinone derivatives as novel inhibitors of the p53–MDM2 interaction with a distinct binding mode

Gessier, François, Kallen, Joerg, Jacoby, Edgar, Chène, Patrick, Stachyra-Valat, Thérèse, Ruetz, Stephan, Jeay, Sébastien, Holzer, Philipp, Masuya, Keiichi, Furet, Pascal

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 1.64 MB

english, 2015

35

Randomized Study of Noninferiority Comparing Prosthetic and Autologous Vein Above-Knee Femoropopliteal Bypasses

Midy, Dominique, Papon, Xavier, Patra, Philippe, Hassen Kodja, Réda, Feugier, Patrick, Plissonnier, Didier, Reix, Thierry, Chene, Geneviève, Berard, Xavier

Journal:

Annals of Vascular Surgery

Year:

2016

Language:

english

File:

PDF, 318 KB

english, 2016

36

Time-Updated CD4+ T Lymphocyte Count and HIV RNA as Major Markers of Disease Progression in Naive HIV-1-Infected Patients Treated With a Highly Active Antiretroviral Therapy

Thiébaut, Rodolphe, Chêne, Geneviève, Jacqmin-Gadda, Hélène, Morlat, Philippe, Mercié, Patrick, Dupon, Michel, Neau, Didier, Ramaroson, Hanta, Dabis, François, Salamon, Roger

Journal:

JAIDS Journal of Acquired Immune Deficiency Syndromes

Year:

2003

File:

PDF, 4.68 MB

2003

37

High frequency of poor locomotor performance in HIV-infected patients

Richert, Laura, Dehail, Patrick, Mercié, Patrick, Dauchy, Frédéric-Antoine, Bruyand, Mathias, Greib, Carine, Dabis, François, Bonnet, Fabrice, Chêne, Geneviève

Journal:

Year:

2011

Language:

english

File:

PDF, 234 KB

english, 2011

38

Prognostic Factors of Combined Viral Load and CD4+ Cell Count Responses Under Triple Antiretroviral Therapy, Aquitaine Cohort, 1996–1998

Marimoutou, Catherine, Chêne, Geneviève, Mercié, Patrick, Neau, Didier, Farbos, Sophie, Morlat, Philippe, Ceccaldi, Joel, Dabis, François

Journal:

JAIDS Journal of Acquired Immune Deficiency Syndromes

Year:

2001

File:

PDF, 500 KB

2001

39

Drugs Targeting Protein–Protein Interactions

Journal:

Year:

2006

Language:

english

File:

PDF, 768 KB

english, 2006

40

In vitro structure-function analysis of the β-strand 326-333 of human p53

Patrick Chène, Peer Mittl, Markus Grütter

Journal:

Journal of Molecular Biology

Year:

1997

Language:

english

File:

PDF, 460 KB

english, 1997

41

Combining Hit Identification Strategies: Fragment-Based and in Silico Approaches to Orally Active 2-Aminothieno[2,3- d ]pyrimidine Inhibitors of the Hsp90 Molecular Chaperone

Brough, Paul A., Barril, Xavier, Borgognoni, Jenifer, Chene, Patrick, Davies, Nicholas G. M., Davis, Ben, Drysdale, Martin J., Dymock, Brian, Eccles, Suzanne A., Garcia-Echeverria, Carlos, Fromont, Ch

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 4.07 MB

english, 2009

42

Use of front face fluorescence for monitoring lipid oxidation during ageing of cakes

Botosoa, Eliot Patrick, Chèné, Christine, Karoui, Romdhane

Journal:

Year:

2013

Language:

english

File:

PDF, 662 KB

english, 2013

43

Dual Specificity of Src Homology 2 Domains for Phosphotyrosine Peptide Ligands

Gay, Brigitte, Furet, Pascal, García-Echeverría, Carlos, Rahuel, Joseph, Chêne, Patrick, Fretz, Heinz, Schoepfer, Joseph, Caravatti, Giorgio

Journal:

Year:

1997

Language:

english

File:

PDF, 142 KB

english, 1997

44

Inhibition of DNA helicases with DNA-competitive inhibitors

Sandy Dubaele, Wolfang Jahnke, Joseph Schoepfer, Jean Fuchs, Patrick Chène

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 174 KB

english, 2006

45

Mutations at Position 277 Modify the DNA-Binding Specificity of Human p53 in Vitro

Journal:

Biochemical and Biophysical Research Communications

Year:

1999

Language:

english

File:

PDF, 138 KB

english, 1999

46

Molecular characterization of the hdm2-p53 interaction

Angelika Böttger, Volker Böttger, Carlos Garcia-Echeverria, Patrick Chène, Heinz-Kurt Hochkeppel, Wayne Sampson, Kiah Ang, Stephanie F. Howard, Steven M. Picksley, David P. Lane

Journal:

Journal of Molecular Biology

Year:

1997

Language:

english

File:

PDF, 497 KB

english, 1997

47

TT virus infection during chronic hepatitis C

Pascale Trimoulet, Victor de Lédinghen, Didier Ekouevi, Pierre-Henri Bernard, Patrick Merel, Geneviève Chêne, Patrice Couzigou, Hervé Fleury

Journal:

American Journal of Gastroenterology

Year:

2000

Language:

english

File:

PDF, 49 KB

english, 2000

48

New Molecular Assays to Predict Occurrence of Cytomegalovirus Disease in Renal Transplant Recipients

Pellegrin, Isabelle, Garrigue, Isabelle, Ekouevi, Didier, Couzi, Lionel, Merville, Pierre, Merel, Patrick, Chene, Geneviève, Schrive, Marie‐Hélène, Trimoulet, Pascale, Lafon, Marie‐Edith, Fleury, Herv

Journal:

The Journal of Infectious Diseases

Year:

2000

Language:

english

File:

PDF, 82 KB

english, 2000

49

Is hepatitis C virus co-infection associated with survival in HIV-infected patients treated by combination antiretroviral therapy?

Rancinan, Corinne, Neau, Didier, Savès, Marianne, Lawson-Ayayi, Sylvie, Bonnet, Fabrice, Mercié, Patrick, Dupon, Michel, Couzigou, Patrice, Dabis, François, Chêne, Geneviève

Journal:

Year:

2002

Language:

english

File:

PDF, 80 KB

english, 2002

50

Prognostic Factors of Combined Viral Load and CD4+ Cell Count Responses Under Triple Antiretroviral Therapy, Aquitaine Cohort, 1996–1998

Marimoutou, Catherine, Chêne, Geneviève, Mercié, Patrick, Neau, Didier, Farbos, Sophie, Morlat, Philippe, Ceccaldi, Joel, Dabis, François

Journal:

JAIDS Journal of Acquired Immune Deficiency Syndromes

Year:

2001

File:

PDF, 500 KB

2001

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